1,1,2-Ethenetricarbonitrile, 2-[4-[bis(2-hydroxyethyl)amino]phenyl]-
[4-[二(2-羟基乙基)氨基]苯基]-1,1,2-乙烯三甲腈
CAS: 56672-91-4
Molecular Formula: C15H14N4O2
1,1,2-Ethenetricarbonitrile, 2-[4-[bis(2-hydroxyethyl)amino]phenyl]- - Names and Identifiers
1,1,2-Ethenetricarbonitrile, 2-[4-[bis(2-hydroxyethyl)amino]phenyl]- - Physico-chemical Properties
| Molecular Formula | C15H14N4O2 |
| Molar Mass | 282.3 |
| Density | 1.326±0.06 g/cm3(Predicted) |
| Melting Point | 72-76°C(lit.) |
| Boling Point | 518.4±50.0 °C(Predicted) |
| pKa | 14.11±0.10(Predicted) |
| Storage Condition | Room Temprature |
1,1,2-Ethenetricarbonitrile, 2-[4-[bis(2-hydroxyethyl)amino]phenyl]- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
1,1,2-Ethenetricarbonitrile, 2-[4-[bis(2-hydroxyethyl)amino]phenyl]- - Introduction
[4-[Bis (2-hydroxyethyl) amino] phenyl]-1,1, 2-ethylenetricarbonitrile, often referred to simply as DEAE-Sepharose. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White to light yellow solid
-Molecular formula: C18H22N2O2
-Molecular weight: 298.38g/mol
-Melting point: >300°C
-Solubility: Soluble in water, soluble in organic solvents such as methanol, acetone and dimethyl sulfoxide
Use:
-[4-[Bis (2-hydroxyethyl) amino] phenyl]-1,1, 2-ethylenetricarbonitrile is an affinity chromatography medium used for separation and purification of proteins. It is mainly used to study the structure and function of proteins, such as the analysis of enzyme activity and the purification of subunits. It can be used to selectively adsorb proteins from complex mixtures and achieve protein elution by changing pH or ion concentration.
Preparation Method:
-Its preparation mainly involves the reaction of [4-[bis (2-chloroethyl) amino] phenyl]-1,1, 2-vinyltricarbonitrile with bis (2-hydroxyethyl) amine to form [4-[bis (2-hydroxyethyl) amino] phenyl]-1,1, 2-vinyltricarbonitrile.
Safety Information:
- [4-[Bis (2-hydroxyethyl) amino] phenyl]-1,1, 2-ethylenetricarbonitrile is a chemical that requires careful handling.
-Avoid contact with skin, eyes and respiratory tract.
-Wear protective gloves, goggles and protective mask when used.
-Ensure good ventilation during operation.
-storage should be stored in a cool, dry place, and away from fire and oxidant.
Please note that the use and handling of chemicals involves safety issues and must follow relevant safe operating procedures and use appropriate personal protective equipment.
Nature:
-Appearance: White to light yellow solid
-Molecular formula: C18H22N2O2
-Molecular weight: 298.38g/mol
-Melting point: >300°C
-Solubility: Soluble in water, soluble in organic solvents such as methanol, acetone and dimethyl sulfoxide
Use:
-[4-[Bis (2-hydroxyethyl) amino] phenyl]-1,1, 2-ethylenetricarbonitrile is an affinity chromatography medium used for separation and purification of proteins. It is mainly used to study the structure and function of proteins, such as the analysis of enzyme activity and the purification of subunits. It can be used to selectively adsorb proteins from complex mixtures and achieve protein elution by changing pH or ion concentration.
Preparation Method:
-Its preparation mainly involves the reaction of [4-[bis (2-chloroethyl) amino] phenyl]-1,1, 2-vinyltricarbonitrile with bis (2-hydroxyethyl) amine to form [4-[bis (2-hydroxyethyl) amino] phenyl]-1,1, 2-vinyltricarbonitrile.
Safety Information:
- [4-[Bis (2-hydroxyethyl) amino] phenyl]-1,1, 2-ethylenetricarbonitrile is a chemical that requires careful handling.
-Avoid contact with skin, eyes and respiratory tract.
-Wear protective gloves, goggles and protective mask when used.
-Ensure good ventilation during operation.
-storage should be stored in a cool, dry place, and away from fire and oxidant.
Please note that the use and handling of chemicals involves safety issues and must follow relevant safe operating procedures and use appropriate personal protective equipment.
Last Update：2024-04-10 22:29:15
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